There are a seemingly infinite number of indie web series chronicling the angst and uncertainty of twentysomethings trying to make it in the big city, but college remains a relatively unexamined setting. This is pretty easy to understand: There isn’t nearly as much potential for conflict in a time marked by bacchanalia and easygoing attitudes.

Out of State, a web series from creator Matt Giudice, makes me wish university was a more popular topic among indie creators. A comedy that recently began its second season, Out of State takes the character-driven humor typical of any good indie series and combines it with a fresher setting.

The series is centered around two friends who become estranged after the morally-loose half of the odd couple sleeps with the uptight half’s crush. There is a strong Scrubs vibe, with lots of internal monologues and a central bromance that drives the plot.

At the same time, Out of State is very much a college web series, and setting is important. The first episode’s main joke revolves around one of our leads’ attempt to find a roommate, as many of the funny callbacks in the first episode refer to characters introduced in that scene.